Treatment Considerations

Prof. Garth L. Nicolson

There are a number of considerations when undergoing therapy for chronic illnesses, including traditional medical approaches as well as integrative medicine approaches that utilize oxygen therapy, herbal therapy, and heat therapy, among others. The Institute for Molecular Medicine is a nonprofit institution and does not make specific recommendations for individual patients, nor does the Institute endorse commercial products. The types of products and procedures listed in this section are potentially useful; however, they are only examples of the types of approaches and substances that could be beneficial to patients with chronic illnesses. Consult your personal physician for advice on exact dosing and schedules, which can vary among individuals.

The information contained in the accompanying material is not intended to replace the advice of a physician or other health care professional. Patients seeking treatments for their conditions should first consult with and seek information from a qualified health care professional.


  • Pathogenic Mycoplasma Infections in Chronic Illnesses: General
    Considerations in Selecting Conventional and Integrative Treatments,
    Prof. Garth L. Nicolson, International Journal of Clinical Medicine, 2019;
    10: 477-522.

  • Considerations when Undergoing Treatment for Chronic Illnesses and Autoimmune Diseases, by Prof. Garth L. Nicolson, Intern. J. Medicine 1998; 1:123-128. Plus Supplemental Suggestions: Prof. Nicolson 9/15/18. pdf_doc

  • Clinical uses of Membrane Lipid Replacement supplements in restoring membrane function and reducing fatigue in chronic diseases and cancer, by Prof. G. L. Nicolson, et al. Discoveries 2016; 4(1): e54. pdf_doc

  • Mitochondrial dysfunction and chronic disease: treatment with Membrane Lipid replacement and other natural supplements, by Prof. Garth L. Nicolson, et al., in Mitochondrial Biology and Experimental THerapeutics 2018; 499-521. pdf_doc

  • Mitochondrial dysfunction and chronic disease: treatment with Membrane Lipid Replacement and other natural supplements, by Prof. Garth L. Nicolson, et al., in: Mitochondrial Biology and Experimental Therapeutics, (P. Oliveira, Ed.), Springer Press, New York, 2018; 499-522. pdf_doc


    (attached as: Mito Dysfunct Treatment-Mito Biology-Nicolson2018.pdf)


  • Membrane Lipid Replacement for chronic illnesses, aging and cancer using oral glycerolphospholipid formulations with fructooligosaccharides to restore phospholipid function in cellular membranes, organelles, cells and tissues, by Prof. Garth L. Nicolson and Michael Ash, Biochimica et Biophysica Acta Biomembranes 2017; 1859: 1704-1724. pdf_doc

  • Mitochondrial dysfunction and chronic disease: treatment with natural supplements, by Prof. Garth L. Nicolson, Altern. Therapies in Health & Medicine 2014; 20(Suppl. 1): 18-25. pdf_doc

  • Clinical effects of hydrogen administration: from animal and human diseases to exercise medicine, by Garth L. Nicolson et al., International Journal of Clinical Medicine 2016; 7: 32-76. pdf_doc

  • Lipid replacement and antioxidant nutritional therapy for restoring mitochondrial function and reducing fatigue in chronic fatigue syndrome and other fatiguing illnesses, by Prof. Nicolson, Journal of Chronic Fatigue Syndrome 2006; 13(1): 57-68. pdf doc

  • Calcium Disodium EDTA Chelation Suppositories: a novel approach for removing heavy metal toxins in clinical practice, by R. Ellithorpe, T. Jimenez, B. Jacques, R. Settineri, L. Calpp and Garth L. Nicolson, In: Anti-Aging Therapeutics, R. Klatz and R. Goldman, eds., vol. 11, American Academy of Anti-Aging Medicine, 2009: 107-118. pdf doc

  • Lipid replacement therapy: a nutraceutical approach for reducing
    cancer-associated fatigue and the adverse effects of cancer therapy while
    restoring mitochondrial function,
    by Prof. Garth Nicolson. Cancer &
    Metastasis Reviews 2010; 29(3): 543-552.
    pdf doc

  • Lipid replacement as an adjunct therapy in chronic fatigue, anti-aging and restoration of mitochondrial function, by G. L. Nicolson, JANA 2003; 6(3): 22-28. pdf doc

  • Nutritional Supplement (NT Factor™) Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects, by M. Agadjanyan, et al. J. Chronic Fatigue Syndr. 2003; 11(3): 23-36. pdf doc

  • Lipid Replacement Therapy with a Glycophospholipid Formulation with NADH and CoQ10 Significantly Reduces Fatigue in Intractable Chronic Fatiguing Illnesses and Chronic Lyme Disease Patients by G. L. Nicolson et al., International Journal of Clinical Medicine 2012; 3: 163-170. pdf doc

  • Diagnosis and Integrative Treatment of Intracellular Bacterial Infections in Chronic Fatigue and Fibromyalgia Syndromes, Gulf War Illness, Rheumatoid Arthritis and other Chronic Illnesses. Clinical Practice of Alternative Medicine 2000; 1(2): 42 - 102 pdf doc

  • Identification and Treatment of Chronic Infections in CFIDS, Fibromyalgia Syndrome and Rheumatoid Arthritis. CFIDS Chronicle 1999; 12(3): 19-21  pdf doc

*PDF files can be opened by obtaining a free copy of Adobe Acrobat from:


  • Notes On Morgellons Syndrome (Disease), Contributors to this information: Cheryl Nichols, Prof. Garth Nicolson, The Institute for Molecular Medicine and The Morgellons Research Foundation, Revised Patient Information (Updated 2/2/09) pdf doc

  • Advanced Topics in Lyme Disease: Diagnostic hints and treatment guidelines for Lyme and other tick borne illnesses by J.J. Burrascano, Jr., Managing Lyme Disease, 16th Edition, 2008. pdf doc

  • Diagnosis and therapy of chronic systemic co-infections in Lyme Disease and other tick-borne infectious diseases, by Prof. Garth Nicolson, Townsend Lett. Doctors  2007; 285: 93-98  pdf doc

  • Treatment Considerations for Autistic Spectrum Disorder Patients at the Institute for Molecular Medicine, by Prof. G. Nicolson, 2006  pdf doc

  • Suggested therapy of chronic systemic Chlamydial and Chlamydial/Mycoplamal co-infections, by Prof. Garth Nicolson, 2005 pdf doc

  • Diagnosis and Therapy of Chronic Systemic Co-Infections in Lyme Disease and Other Tick-Borne Infectious Diseases, American College for Advancement in Medicine, by Prof. Garth Nicolson, 2006  rtf doc

  • Chronic Fatigue, Aging, Mitochondrial Function and Nutritiional Supplements, by Prof. Garth Nicolson, Townsend Letter for Doctors & Patients 2003; 240(7): 72-76. pdf_doc

  • Fighting Those Persistent INFECTIONS In CFIDS By Jacob Teitelbaum, From Fatigued to Fantastic Newsletter 2000; 3 and 2001; 4 newsletters rtf doc

  • Research Overview: Professor Garth Nicolson's Studies and Treatments Explained By Deborah Cooper, Treatment & Research Library, 2006  rtf  doc

  • Why I Prescribe Antibiotics. By Gabe Mirkin, M.D., 2000 rtf doc

  • Dietary Considerations for Patients with Chronic Illnesses and Multiple Chronic Infections: A Brief Outline of Eighteen Dietary Steps to Better Health by Garth Nicolson and Richard Ngwenya, Towsend Lett. Doctors 2001; 219:62-65. pdf doc

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